James Uniacke, PhD, is an Assistant Professor in the Department of Cellular and Molecular Biology at the University of Guelph where his lab studies protein translation machinery.
Here, Alicia talks with Jim about his group’s recent publication in JBC, “Human Cells Cultured under Physiological Oxygen Utilize Two Cap-binding Proteins to Recruit Distinct mRNAs for Translation.”  This interview discussing how differing molecular mechanisms can result from varied physiological conditions was edited for length.
Even with proper procedures, lab workers are still at risk for becoming infected. Discover some ways to reduce laboratory-acquired infections below.
Two documented cases of laboratory-acquired infections (LAI) have made it into the popular media this year alone, one in Europe and one at the CDC. In both of these cases, workers doing routine work with standard procedures somehow became infected with biological materials they handled and nobody knows how.
We would all like to think that LAI are quite rare, but they still happen, so the risk is still there for all laboratory workers, both in the clinical and the research setting.
This is final part in a three-part series of blog posts containing excerpts from an interview that Dr. Alicia Henn, Chief Scientific Officer of BioSpherix, conducted with Dr. Heather O’Leary. In the third and final part of our interview, we sit with Dr. Heather O’Leary to discuss how room air oxygen conditions affect cell research.
In the last post, Dr. O’Leary talked with us about specific technical challenges in working with cells in low oxygen. Here we talk about terminology for physiologically relevant oxygen studies and whether or not room air is “good enough.”
This is Part Two in a three-part series of blog posts from an interview that Dr. Alicia Henn, Chief Scientific Officer of BioSpherix, conducted with Dr. Heather O’Leary. Our conversation was edited for length and clarity.
In Part One, Heather told us about why her work is so exciting. Today, Heather talks with us about practical considerations that might limit researchers wanting to keep their cells in low-oxygen.
This is a three-part series of blog posts containing excerpts from an interview that Dr. Alicia Henn, Chief Scientific Officer of BioSpherix, conducted with Dr. Heather Ann O’Leary. Dr. O’Leary has finished up a post-doc in the laboratory of Hal Broxmeyer and is starting up her own lab at Indiana University. Her talk was a highlight of ISSCR 2015 where she reported on a landmark paper published in Cell.  Our conversation was edited for length and clarity. Continue reading the interview transcripts to learn more about her findings regarding how hematopoietic stem cells are affected by EPHOSS.